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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: O75223




USC-OGP 2-DE database:  O75223


O75223


General information about the entry
View entry in simple text format
Entry nameGGCT_HUMAN
Primary accession numberO75223
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Gamma-glutamylcyclotransferase; EC=2.3.2.4; AltName: Full=Cytochrome c-releasing factor 21;.
Gene nameName=GGCT
Synonyms=C7orf24, CRF21
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info
 
PLATELET_4-5

MAP LOCATIONS:
pI=5.00; Mw=20827



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=5.02; Mw=22379

Cross-references
UniProtKB/Swiss-ProtO75223; GGCT_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameGGCT_HUMAN
Primary accession numberO75223
Secondary accession number(s) B2RDN0 B8ZZN4 B8ZZR8 Q9BS37
Sequence was last modified on November 1, 1998 (version 1)
Annotations were last modified on March 15, 2017 (version 129)
Name and origin of the protein
DescriptionRecName: Full=Gamma-glutamylcyclotransferase; EC=2.3.2.4; AltName: Full=Cytochrome c-releasing factor 21;
Gene nameName=GGCT
Synonyms=C7orf24, CRF21
Encoded onName=GGCT; Synonyms=C7orf24, CRF21
Keywords3D-structure; Acyltransferase; Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAK315608; BAG37977.1; -; mRNA
EMBLAC005154; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471073; EAW93950.1; -; Genomic_DNA
EMBLCH471073; EAW93952.1; -; Genomic_DNA
EMBLCH471073; EAW93953.1; -; Genomic_DNA
EMBLBC000625; AAH00625.1; -; mRNA
EMBLBC005356; AAH05356.1; -; mRNA
EMBLBC013937; AAH13937.1; -; mRNA
EMBLBC019243; AAH19243.1; -; mRNA
CCDSCCDS5428.1; -. [O75223-1]; .
CCDSCCDS56474.1; -. [O75223-3]; .
CCDSCCDS56475.1; -. [O75223-2]; .
CCDSCCDS56476.1; -. [O75223-4]; .
RefSeqNP_001186744.1; NM_001199815.1. [O75223-4]; .
RefSeqNP_001186745.1; NM_001199816.1. [O75223-2]; .
RefSeqNP_001186746.1; NM_001199817.1. [O75223-3]; .
RefSeqNP_076956.1; NM_024051.3. [O75223-1]; .
UniGeneHs.530024; -; .
PDB2I5T; X-ray; 2.01 A; A/B=2-188
PDB2PN7; X-ray; 2.41 A; A/B=1-188
PDB2Q53; X-ray; 2.01 A; A/B=2-188
PDB2RBH; X-ray; 2.10 A; A/B=1-188
PDB3CRY; X-ray; 1.70 A; A/B=1-188
PDBsum2I5T; -; .
PDBsum2PN7; -; .
PDBsum2Q53; -; .
PDBsum2RBH; -; .
PDBsum3CRY; -; .
ProteinModelPortalO75223; -; .
SMRO75223; -; .
BioGrid122486; 10; .
IntActO75223; 7; .
STRING9606.ENSP00000275428; -; .
iPTMnetO75223; -; .
PhosphoSitePlusO75223; -; .
BioMutaGGCT; -; .
OGPO75223; -; .
EPDO75223; -; .
MaxQBO75223; -; .
PaxDbO75223; -; .
PeptideAtlasO75223; -; .
PRIDEO75223; -; .
DNASU79017; -; .
EnsemblENST00000005374; ENSP00000005374; ENSG00000006625. [O75223-2]; .
EnsemblENST00000275428; ENSP00000275428; ENSG00000006625. [O75223-1]; .
EnsemblENST00000409144; ENSP00000386610; ENSG00000006625. [O75223-3]; .
EnsemblENST00000409390; ENSP00000387235; ENSG00000006625. [O75223-4]; .
GeneID79017; -; .
KEGGhsa:79017; -; .
UCSCuc003tba.4; human. [O75223-1]; .
CTD79017; -; .
DisGeNET79017; -; .
GeneCardsGGCT; -; .
HGNCHGNC:21705; GGCT; .
HPAHPA020735; -; .
HPAHPA029914; -; .
MIM137170; gene; .
neXtProtNX_O75223; -; .
OpenTargetsENSG00000006625; -; .
PharmGKBPA162389392; -; .
eggNOGKOG4059; Eukaryota; .
eggNOGENOG4111IGG; LUCA; .
GeneTreeENSGT00500000044921; -; .
HOGENOMHOG000008049; -; .
HOVERGENHBG050922; -; .
InParanoidO75223; -; .
KOK00682; -; .
OMARCPHSPM; -; .
OrthoDBEOG091G0NMM; -; .
PhylomeDBO75223; -; .
TreeFamTF314378; -; .
BRENDA2.3.2.4; 2681; .
ReactomeR-HSA-174403; Glutathione synthesis and recycling; .
ChiTaRSGGCT; human; .
EvolutionaryTraceO75223; -; .
GenomeRNAi79017; -; .
PROPR:O75223; -; .
ProteomesUP000005640; Chromosome 7; .
BgeeENSG00000006625; -; .
CleanExHS_GGCT; -; .
ExpressionAtlasO75223; baseline and differential; .
GenevisibleO75223; HS; .
GOGO:0005829; C:cytosol; IDA:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0003839; F:gamma-glutamylcyclotransferase activity; IDA:UniProtKB; .
GOGO:0042803; F:protein homodimerization activity; IDA:UniProtKB; .
GOGO:0006750; P:glutathione biosynthetic process; TAS:Reactome; .
GOGO:0001836; P:release of cytochrome c from mitochondria; IMP:UniProtKB; .
CDDcd06661; GGCT_like; 1; .
Gene3D3.10.490.10; -; 1; .
InterProIPR017939; G-Glutamylcylcotransferase; .
InterProIPR013024; GGCT-like; .
PANTHERPTHR12935; PTHR12935; 1; .
SUPFAMSSF110857; SSF110857; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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